OCCURRENCE OF ESCHERICHIA COLI CARRYING SHIGA TOXIN-PRODUCING GENES IN BUFFALOES ON SMALLHOLDINGS IN BANGLADESH

Occurrence of Escherichia coli carrying Shiga toxin-producing genes in buffaloes on smallholdings in Bangladesh

Background and Aim: Shiga toxin-producing Escherichia coli (STEC) has emerged as significant foodborne pathogens.Ruminants are the primary reservoir of the zoonotic STEC.In Bangladesh, previous studies reported the presence of STEC in cattle, goat, and sheep; however, there is little information about STEC carriage by buffaloes.This study aimed to

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The Multifaceted Roles of NRF2 in Cancer: Friend or Foe?

Physiological concentrations of reactive oxygen species (ROS) play vital roles in various normal cellular processes, whereas excessive ROS generation is central to disease pathogenesis.The nuclear factor erythroid 2-related factor 2 (NRF2) is a critical transcription factor that regulates the cellular antioxidant systems in response to oxidative st

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New open-source software for subcellular segmentation and analysis of spatiotemporal fluorescence signals using deep learning

Summary: Cellular imaging instrumentation advancements as well as readily available optogenetic and fluorescence sensors have yielded a profound need for fast, accurate, and standardized analysis.Deep-learning architectures have revolutionized the field of biomedical image analysis and have achieved state-of-the-art accuracy.Despite these advanceme

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Specification and spatial arrangement of cells in the germline stem cell niche of the Drosophila ovary depend on the Maf transcription factor Traffic jam.

Germline stem cells in the Drosophila ovary are maintained by a somatic niche.The niche is structurally and functionally complex and contains four cell types, the escort, cap, and terminal filament cells and the newly identified transition cell.We find that the large Maf transcription factor Traffic jam (Tj) is essential for determining niche cell

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